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C4 Test (C4 Complement) and its Function

The C4 test, also known as the C4 complement test, is a laboratory test used to measure the levels of C4 complement component in the blood. The complement system is a part of the immune system that helps in the defense against infections and the clearance of immune complexes from the body. The C4 complement component is one of the proteins involved in the complement cascade, which is a series of reactions that help in the immune response.

Conditions that may require C4 Test (C4 Complement)

Suspected Complement Deficiencies: Certain medical conditions, such as hereditary angioedema and systemic lupus erythematosus (SLE), are associated with deficiencies or dysfunctions in complement components, including C4. The C4 test can help in the diagnosis and monitoring of these conditions.
Monitoring Disease Activity: In autoimmune diseases like SLE, the C4 test may be used to monitor disease activity and response to treatment. Decreased C4 levels can indicate disease flare-ups, while increased levels may suggest improvement.
Evaluation of Kidney Disorders: Some kidney diseases, such as systemic lupus nephritis, can involve complement system activation and C4 consumption. The C4 test may be used to assess complement system involvement in these conditions.

C4 Test (C4 Complement) Procedure

The C4 Test (C4 Complement) is a simple blood test that can be performed in a laboratory. Before the test, the patient may be asked to avoid certain medications that may affect the results. During the test, our healthcare professional will use a needle to draw blood from a vein in the patient's arm. The blood sample will then be sent to our laboratory for analysis.

Interpreting C4 Test (C4 Complement) Results

Interpreting C4 test results involves comparing the measured levels of C4 with established reference ranges. Low C4 levels may indicate complement deficiencies, ongoing complement activation, or consumption. Elevated C4 levels may suggest increased complement activation or certain inflammatory conditions.