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C3 Test (C3 Complement) and its Function

The C3 test, also known as the C3 complement test, is a laboratory test used to measure the levels of C3 complement component in the blood. The complement system is a part of the immune system that helps in the defense against infections and the clearance of immune complexes from the body. The C3 complement component plays a crucial role in the complement cascade, which is a series of reactions that help in the immune response.

Conditions that may require C3 Test (C3 Complement)

Suspected Complement Deficiencies: Certain medical conditions, such as hereditary angioedema and systemic lupus erythematosus (SLE), are associated with deficiencies or dysfunctions in complement components, including C3. The C3 test can help in the diagnosis and monitoring of these conditions.
Monitoring Disease Activity: In autoimmune diseases like SLE, the C3 test may be used to monitor disease activity and response to treatment. Decreased C3 levels can indicate disease flare-ups, while increased levels may suggest improvement.
Evaluation of Kidney Disorders: Some kidney diseases, such as membranoproliferative glomerulonephritis (MPGN) and lupus nephritis, can involve complement system activation and C3 consumption. The C3 test may be used to assess complement system involvement in these conditions.

C3 Test (C3 Complement) Procedure

The C3 Test (C3 Complement) is a simple blood test that can be performed in a laboratory. Before the test, the patient may be asked to avoid certain medications that may affect the results. During the test, our healthcare professional will use a needle to draw blood from a vein in the patient's arm. The blood sample will then be sent to our laboratory for analysis.

Interpreting C3 Test (C3 Complement) Results

Interpreting C3 test results involves comparing the measured levels of C3 with established reference ranges. Low C3 levels may indicate complement deficiencies, ongoing complement activation, or consumption. Elevated C3 levels may suggest increased complement activation or certain inflammatory conditions.